Molecule graphic

A Next-Gen Polymer Therapeutic

1
Immunogenicity

Does not elicit an immune response or stimulate development of antibodies

2
Drug Loading

Enables considerably greater drug loading with almost all drugs – current focus on phenolic hydroxyls

3
Release

Programmable drug release kinetics enable continuous delivery

4
Accumulation

Does not accumulate in tissues, is not metabolized, clears through renal filtration

5
Synthesis and Stability

Uses safe, inexpensive materials in a “one pot” synthesis and is stable at room temperature

Enabling Continuous Drug Delivery and Why It Matters

Many drugs, for example those used to treat neurological disorders like Parkinson’s, have narrow therapeutic ranges in which they can work safely and efficaciously. They are often dosed more frequently – resulting in large and frequent fluctuations in drug exposure. They have to be monitored and dose adjusted with greater frequency, and on an individual basis. These fluctuations present clinical, compliance and quality of life challenges for many patients.

Administered Subcutaneously, POZ Provides Extended Delivery

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